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TB vaccine from the 1920s shows promise in diabetes trial
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TB vaccine from the 1920s shows promise in diabetes trial.The Bacillus Calmette–Guérin vaccine, often given to infants in countries with high rates of tuberculosis, is also being tested as a treatment for diabetes, Alzheimer’s disease and other conditions.Credit: Nikolay Doycinov/AFP via Getty A century-old vaccine against tuberculosis helps to regulate blood sugar in people with certain types of diabetes, such that they can reduce their insulin use, according to the results of a phase II clinical trial.The finding adds support for the once-controversial hypothesis that vaccines made with living but weakened pathogens can protect against both their target disease and off-target ones.Hope for diabetes: CRISPR-edited cells pump out insulin in a person – and evade immune detection